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RNA polymerase alpha subunit recognizes the DNA shape of the Upstream Promoter element
We demonstrate here that the alpha subunit C-terminal domain of E. coli RNA polymerase (αCTD) recognizes the upstream promoter (UP) DNA element via its characteristic minor groove shape and electrostatic potential. In two compositionally distinct crystallized assemblies, a pair of αCTD subunits bind...
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| Publicado no: | Biochemistry |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8100869/ https://ncbi.nlm.nih.gov/pubmed/33205945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00571 |
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