RNA polymerase alpha subunit recognizes the DNA shape of the Upstream Promoter element

We demonstrate here that the alpha subunit C-terminal domain of E. coli RNA polymerase (αCTD) recognizes the upstream promoter (UP) DNA element via its characteristic minor groove shape and electrostatic potential. In two compositionally distinct crystallized assemblies, a pair of αCTD subunits bind...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Biochemistry
Main Authors: Lara-Gonzalez, Samuel, Machado, Ana Carolina Dantas, Rao, Satyanarayan, Napoli, Andrew A., Birktoft, Jens, Di Felice, Rosa, Rohs, Remo, Lawson, Catherine L.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8100869/
https://ncbi.nlm.nih.gov/pubmed/33205945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.0c00571
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki