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Colonic epithelial adaptation to EGFR-independent growth induces chromosomal instability and is accelerated by prior injury
Although much is known about the gene mutations required to drive colorectal cancer (CRC) initiation, the tissue-specific selective microenvironments in which neoplasia arises remains less characterized. Here, we determined whether modulation of intestinal stem cell niche morphogens alone can exert...
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| Publicado no: | Neoplasia |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Neoplasia Press
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8099723/ https://ncbi.nlm.nih.gov/pubmed/33906087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2021.03.010 |
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