Aurora-A Expression Is Independently Associated with Chromosomal Instability in Colorectal Cancer

AURKA (the official symbol for Aurora-A, STK15, or BTAK) regulates the function of centrosomes, spindles, and kinetochores for proper mitotic progression. AURKA overexpression is observed in various cancers including colon cancer, and a link between AURKA and chromosomal instability (CIN) has been p...

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Hauptverfasser: Baba, Yoshifumi, Nosho, Katsuhiko, Shima, Kaori, Irahara, Natsumi, Kure, Shoko, Toyoda, Saori, Kirkner, Gregory J, Goel, Ajay, Fuchs, Charles S, Ogino, Shuji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Neoplasia Press Inc. 2009
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2671854/
https://ncbi.nlm.nih.gov/pubmed/19412426
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