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Forebrain-specific deficiency of the GTPase CRAG/Centaurin-γ3 leads to immature dentate gyri and hyperactivity in mice

Mouse models of various neuropsychiatric disorders, such as schizophrenia, often display an immature dentate gyrus, characterized by increased numbers of immature neurons and neuronal progenitors and a dearth of mature neurons. We previously demonstrated that the CRMP5-associated GTPase (CRAG), a sh...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Nagashima, Shun, Ito, Naoki, Kobayashi, Reiki, Shiiba, Isshin, Shimura, Hiroki, Fukuda, Toshifumi, Hagihara, Hideo, Miyakawa, Tsuyoshi, Inatome, Ryoko, Yanagi, Shigeru
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099661/
https://ncbi.nlm.nih.gov/pubmed/33811862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100620
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