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Forebrain-specific deficiency of the GTPase CRAG/Centaurin-γ3 leads to immature dentate gyri and hyperactivity in mice

Mouse models of various neuropsychiatric disorders, such as schizophrenia, often display an immature dentate gyrus, characterized by increased numbers of immature neurons and neuronal progenitors and a dearth of mature neurons. We previously demonstrated that the CRMP5-associated GTPase (CRAG), a sh...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Nagashima, Shun, Ito, Naoki, Kobayashi, Reiki, Shiiba, Isshin, Shimura, Hiroki, Fukuda, Toshifumi, Hagihara, Hideo, Miyakawa, Tsuyoshi, Inatome, Ryoko, Yanagi, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099661/
https://ncbi.nlm.nih.gov/pubmed/33811862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jbc.2021.100620
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