CRMP5-associated GTPase (CRAG) Protein Protects Neuronal Cells against Cytotoxicity of Expanded Polyglutamine Protein Partially via c-Fos-dependent Activator Protein-1 Activation

We previously demonstrated that CRAM (CRMP5)-associated GTPase (CRAG), a short splicing variant of centaurin-γ3/AGAP3, facilitated degradation of expanded polyglutamine protein (polyQ) via the nuclear ubiquitin-proteasome pathway. Taking advantage of this feature, we also showed that lentivirus-medi...

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Detalhes bibliográficos
Principais autores: Nagashima, Shun, Fukuda, Toshifumi, Kubota, Yuka, Sugiura, Ayumu, Nakao, Mitsuyoshi, Inatome, Ryoko, Yanagi, Shigeru
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3190814/
https://ncbi.nlm.nih.gov/pubmed/21832068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.234997
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