Rolling-translated EGFR variants sustain EGFR signaling and promote glioblastoma tumorigenicity

BACKGROUND: Aberrant epidermal growth factor receptor (EGFR) activation is observed in over 50% of cases of adult glioblastoma (GBM). Nevertheless, EGFR antibodies are ineffective in clinical GBM treatment, suggesting the existence of redundant EGFR activation mechanisms. Whether circular RNA (circR...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Liu, Yi, Li, Zhongjun, Zhang, Maolei, Zhou, Huangkai, Wu, Xujia, Zhong, Jian, Xiao, Feizhe, Huang, Nunu, Yang, Xuesong, Zeng, Rong, Yang, Lixuan, Xia, Zhibo, Zhang, Nu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099477/
https://ncbi.nlm.nih.gov/pubmed/33325513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noaa279
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados