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A non-hierarchical organization of tumorigenic NG2 cells in glioblastoma promoted by EGFR

BACKGROUND: Expression of neuron-glial antigen 2 (NG2) identifies an aggressive malignant phenotype in glioblastoma (GBM). Mouse models have implicated NG2 in the genesis, evolution, and maintenance of glial cancers and have highlighted potential interactions between NG2 and epidermal growth factor...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Al-Mayhani, Talal F, Heywood, Richard M, Vemireddy, Vamsidhara, Lathia, Justin D, Piccirillo, Sara G M, Watts, Colin
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765068/
https://ncbi.nlm.nih.gov/pubmed/30590711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy204
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