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Network model‐based screen for FDA‐approved drugs affecting cardiac fibrosis

Cardiac fibrosis is a significant component of pathological heart remodeling, yet it is not directly targeted by existing drugs. Systems pharmacology approaches have the potential to provide mechanistic frameworks with which to predict and understand how drugs modulate biological systems. Here, we c...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:CPT Pharmacometrics Syst Pharmacol
Egile Nagusiak: Zeigler, Angela C., Chandrabhatla, Anirudha S., Christiansen, Steven L., Nelson, Anders R., Holmes, Jeffrey W., Saucerman, Jeffrey J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: John Wiley and Sons Inc. 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099443/
https://ncbi.nlm.nih.gov/pubmed/33571402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12599
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