A screen of FDA-approved drugs for inhibitors of Zika virus infection

Currently there are no approved vaccines or specific therapies to prevent or treat Zika virus (ZIKV) infection. We interrogated a library of FDA-approved drugs for their ability to block infection of human HuH-7 cells by a newly isolated ZIKV strain (ZIKV MEX_I_7). More than 20 out of 774 tested com...

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Udgivet i:Cell Host Microbe
Main Authors: Barrows, Nicholas J., Campos, Rafael K., Powell, Steven, Prasanth, K. Reddisiva, Schott-Lerner, Geraldine, Soto-Acosta, Ruben, Galarza-Muñoz, Gaddiel, McGrath, Erica L., Urrabaz-Garza, Rheanna, Gao, Junling, Wu, Ping, Menon, Ramkumar, Saade, George, Fernandez-Salas, Ildefonso, Rossi, Shannan L., Vasilakis, Nikos, Routh, Andrew, Bradrick, Shelton S., Garcia-Blanco, Mariano A.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4993926/
https://ncbi.nlm.nih.gov/pubmed/27476412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.07.004
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