The SP‐TLR axis, which locally primes the nasal mucosa, is impeded in patients with allergic rhinitis

BACKGROUND: Substance P (SP) and toll‐like receptors (TLRs) contribute to airway disease, particularly during viral infection. We recently demonstrated that SP can act as an initial response to viral stimuli in the upper airway by upregulating TLRs in the nasal epithelia (the SP‐TLR axis). Patients...

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Bibliographische Detailangaben
Veröffentlicht in:Clin Transl Allergy
Hauptverfasser: Larsson, Olivia, Sunnergren, Ola, Bachert, Claus, Kumlien Georén, Susanna, Cardell, Lars Olaf
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2021
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099340/
https://ncbi.nlm.nih.gov/pubmed/33900054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clt2.12009
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