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The SP‐TLR axis, which locally primes the nasal mucosa, is impeded in patients with allergic rhinitis

BACKGROUND: Substance P (SP) and toll‐like receptors (TLRs) contribute to airway disease, particularly during viral infection. We recently demonstrated that SP can act as an initial response to viral stimuli in the upper airway by upregulating TLRs in the nasal epithelia (the SP‐TLR axis). Patients...

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Dettagli Bibliografici
Pubblicato in:Clin Transl Allergy
Autori principali: Larsson, Olivia, Sunnergren, Ola, Bachert, Claus, Kumlien Georén, Susanna, Cardell, Lars Olaf
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099340/
https://ncbi.nlm.nih.gov/pubmed/33900054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clt2.12009
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