The SP‐TLR axis, which locally primes the nasal mucosa, is impeded in patients with allergic rhinitis

BACKGROUND: Substance P (SP) and toll‐like receptors (TLRs) contribute to airway disease, particularly during viral infection. We recently demonstrated that SP can act as an initial response to viral stimuli in the upper airway by upregulating TLRs in the nasal epithelia (the SP‐TLR axis). Patients...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Clin Transl Allergy
Prif Awduron: Larsson, Olivia, Sunnergren, Ola, Bachert, Claus, Kumlien Georén, Susanna, Cardell, Lars Olaf
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: John Wiley and Sons Inc. 2021
Pynciau:
Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099340/
https://ncbi.nlm.nih.gov/pubmed/33900054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clt2.12009
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