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The SP‐TLR axis, which locally primes the nasal mucosa, is impeded in patients with allergic rhinitis

BACKGROUND: Substance P (SP) and toll‐like receptors (TLRs) contribute to airway disease, particularly during viral infection. We recently demonstrated that SP can act as an initial response to viral stimuli in the upper airway by upregulating TLRs in the nasal epithelia (the SP‐TLR axis). Patients...

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Publicado en:Clin Transl Allergy
Autores principales: Larsson, Olivia, Sunnergren, Ola, Bachert, Claus, Kumlien Georén, Susanna, Cardell, Lars Olaf
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2021
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099340/
https://ncbi.nlm.nih.gov/pubmed/33900054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clt2.12009
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