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The SP‐TLR axis, which locally primes the nasal mucosa, is impeded in patients with allergic rhinitis

BACKGROUND: Substance P (SP) and toll‐like receptors (TLRs) contribute to airway disease, particularly during viral infection. We recently demonstrated that SP can act as an initial response to viral stimuli in the upper airway by upregulating TLRs in the nasal epithelia (the SP‐TLR axis). Patients...

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Bibliografiske detaljer
Udgivet i:Clin Transl Allergy
Main Authors: Larsson, Olivia, Sunnergren, Ola, Bachert, Claus, Kumlien Georén, Susanna, Cardell, Lars Olaf
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2021
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8099340/
https://ncbi.nlm.nih.gov/pubmed/33900054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/clt2.12009
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