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Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the molecular mechanism that drives spindle elongation in human cells is unknown. Using combined depletion and...

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Dades bibliogràfiques
Publicat a:Dev Cell
Autors principals: Vukušić, Kruno, Ponjavić, Ivana, Buđa, Renata, Risteski, Patrik, Tolić, Iva M.
Format: Artigo
Idioma:Inglês
Publicat: Cell Press 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098747/
https://ncbi.nlm.nih.gov/pubmed/33910056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.04.005
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