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Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the molecular mechanism that drives spindle elongation in human cells is unknown. Using combined depletion and...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Vukušić, Kruno, Ponjavić, Ivana, Buđa, Renata, Risteski, Patrik, Tolić, Iva M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098747/
https://ncbi.nlm.nih.gov/pubmed/33910056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.04.005
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