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Microtubule-sliding modules based on kinesins EG5 and PRC1-dependent KIF4A drive human spindle elongation

Proper chromosome segregation into two future daughter cells requires the mitotic spindle to elongate in anaphase. However, although some candidate proteins are implicated in this process, the molecular mechanism that drives spindle elongation in human cells is unknown. Using combined depletion and...

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Bibliografische gegevens
Gepubliceerd in:Dev Cell
Hoofdauteurs: Vukušić, Kruno, Ponjavić, Ivana, Buđa, Renata, Risteski, Patrik, Tolić, Iva M.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2021
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098747/
https://ncbi.nlm.nih.gov/pubmed/33910056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2021.04.005
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