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Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes

During cell division, mitotic spindle microtubules segregate chromosomes by exerting forces on kinetochores. What forces drive chromosome segregation in anaphase remains a central question. The current model for anaphase in human cells includes shortening of kinetochore fibers and separation of spin...

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Detalhes bibliográficos
Publicado no:Dev Cell
Main Authors: Vukušić, Kruno, Buđa, Renata, Bosilj, Agneza, Milas, Ana, Pavin, Nenad, Tolić, Iva M.
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637169/
https://ncbi.nlm.nih.gov/pubmed/29017027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.09.010
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