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Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes

During cell division, mitotic spindle microtubules segregate chromosomes by exerting forces on kinetochores. What forces drive chromosome segregation in anaphase remains a central question. The current model for anaphase in human cells includes shortening of kinetochore fibers and separation of spin...

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Bibliografiske detaljer
Udgivet i:Dev Cell
Main Authors: Vukušić, Kruno, Buđa, Renata, Bosilj, Agneza, Milas, Ana, Pavin, Nenad, Tolić, Iva M.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637169/
https://ncbi.nlm.nih.gov/pubmed/29017027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.09.010
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