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Microtubule Sliding within the Bridging Fiber Pushes Kinetochore Fibers Apart to Segregate Chromosomes

During cell division, mitotic spindle microtubules segregate chromosomes by exerting forces on kinetochores. What forces drive chromosome segregation in anaphase remains a central question. The current model for anaphase in human cells includes shortening of kinetochore fibers and separation of spin...

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Vydáno v:Dev Cell
Hlavní autoři: Vukušić, Kruno, Buđa, Renata, Bosilj, Agneza, Milas, Ana, Pavin, Nenad, Tolić, Iva M.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5637169/
https://ncbi.nlm.nih.gov/pubmed/29017027
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2017.09.010
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