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Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces

During metaphase, chromosome position at the spindle equator is regulated by the forces exerted by kinetochore microtubules and polar ejection forces. However, the role of forces arising from mechanical coupling of sister kinetochore fibers with bridging fibers in chromosome alignment is unknown. He...

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Pubblicato in:eLife
Autori principali: Jagrić, Mihaela, Risteski, Patrik, Martinčić, Jelena, Milas, Ana, Tolić, Iva M
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2021
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924949/
https://ncbi.nlm.nih.gov/pubmed/33480356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61170
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