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Optogenetic control of PRC1 reveals its role in chromosome alignment on the spindle by overlap length-dependent forces

During metaphase, chromosome position at the spindle equator is regulated by the forces exerted by kinetochore microtubules and polar ejection forces. However, the role of forces arising from mechanical coupling of sister kinetochore fibers with bridging fibers in chromosome alignment is unknown. He...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Jagrić, Mihaela, Risteski, Patrik, Martinčić, Jelena, Milas, Ana, Tolić, Iva M
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7924949/
https://ncbi.nlm.nih.gov/pubmed/33480356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.61170
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