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p14 (ARF) Deletion and Methylation in Genetic Pathways to Glioblastomas

The CDKN2A locus on chromosome 9p21 contains the p14 (ARF) and p16 (INK4a) genes, and is frequently deleted in human neoplasms, including brain tumors. In this study, we screened 34 primary (de novo) glioblastomas and 16 secondary glioblastomas that had progressed from low‐grade diffuse astrocytomas...

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Dades bibliogràfiques
Publicat a:Brain Pathol
Autors principals: Nakamura, Mitsutoshi, Watanabe, Takao, Klangby, Ulf, Asker, Charlotte, Wiman, Klas, Yonekawa, Yasuhiro, Kleihues, Paul, Ohgaki, Hiroko
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Ltd 2006
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098332/
https://ncbi.nlm.nih.gov/pubmed/11303791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2001.tb00388.x
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