p14 (ARF) Deletion and Methylation in Genetic Pathways to Glioblastomas

The CDKN2A locus on chromosome 9p21 contains the p14 (ARF) and p16 (INK4a) genes, and is frequently deleted in human neoplasms, including brain tumors. In this study, we screened 34 primary (de novo) glioblastomas and 16 secondary glioblastomas that had progressed from low‐grade diffuse astrocytomas...

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Detalhes bibliográficos
Publicado no:Brain Pathol
Main Authors: Nakamura, Mitsutoshi, Watanabe, Takao, Klangby, Ulf, Asker, Charlotte, Wiman, Klas, Yonekawa, Yasuhiro, Kleihues, Paul, Ohgaki, Hiroko
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098332/
https://ncbi.nlm.nih.gov/pubmed/11303791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2001.tb00388.x
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