p14 (ARF) Deletion and Methylation in Genetic Pathways to Glioblastomas

The CDKN2A locus on chromosome 9p21 contains the p14 (ARF) and p16 (INK4a) genes, and is frequently deleted in human neoplasms, including brain tumors. In this study, we screened 34 primary (de novo) glioblastomas and 16 secondary glioblastomas that had progressed from low‐grade diffuse astrocytomas...

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Bibliografiske detaljer
Udgivet i:Brain Pathol
Main Authors: Nakamura, Mitsutoshi, Watanabe, Takao, Klangby, Ulf, Asker, Charlotte, Wiman, Klas, Yonekawa, Yasuhiro, Kleihues, Paul, Ohgaki, Hiroko
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2006
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8098332/
https://ncbi.nlm.nih.gov/pubmed/11303791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2001.tb00388.x
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