Angiotensin II upregulates RANKL/NFATC1 expression in synovial cells from patients with rheumatoid arthritis through the ERK1/2 and JNK pathways

BACKGROUND: Angiotensin II (Ang II) is associated with rheumatoid arthritis (RA) development. The present study investigated the impact of Ang II on the expression of receptor activator of nuclear factor-κB ligand (RANKL), as well as of nuclear factor of activated T cells cytoplasmic 1 (NFATC1) in R...

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Vydáno v:J Orthop Surg Res
Hlavní autoři: Zhao, Zhiping, Zhang, Yongtao, Wang, Changyao, Wang, Xiangyu, Wang, Yingzhen, Zhang, Haining
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2021
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097914/
https://ncbi.nlm.nih.gov/pubmed/33952303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13018-021-02451-0
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