Effects of the Local Bone Renin-Angiotensin System on Titanium-Particle-Induced Periprosthetic Osteolysis

Wear particles may induce osteoclast formation and osteoblast inhibition that lead to periprosthetic osteolysis (PPOL) and subsequent aseptic loosening, which is the primary reason for total joint arthroplasty failure. Local bone renin-angiotensin system (RAS) has been found to participate in the pa...

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Bibliografiska uppgifter
I publikationen:Front Pharmacol
Huvudupphovsmän: Zhao, Zhiping, Wang, Changyao, Xu, Yingxing, Wang, Xiangyu, Jia, Bin, Yu, Tengbo, Wang, Yingzhen, Zhang, Yongtao
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8264785/
https://ncbi.nlm.nih.gov/pubmed/34248634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2021.684375
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