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Periprosthetic Osteolysis: Characterizing the innate immune response to titanium wear-particles

Osteolysis of bone following total hip replacements is a major clinical problem. Examination of the areas surrounding failed implants has indicated an increase in the bone-resorption-inducing cytokine, interleukin 1β (IL-1β). NALP3, a NOD-like receptor protein located in the cytosol of macrophages,...

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Autors principals: St Pierre, Christine A., Chan, Melvin, Iwakura, Yoichiro, Ayers, David C., Kurt-Jones, Evelyn A., Finberg, Robert W.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4011639/
https://ncbi.nlm.nih.gov/pubmed/20872576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jor.21149
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