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Anti-inflammatory drug-eluting implant model system to prevent wear particle-induced periprosthetic osteolysis

BACKGROUND: Aseptic loosening, as a consequence of an extended inflammatory reaction induced by wear particles, has been classified as one of the most common complications of total joint replacement (TJR). Despite its high incidence, no therapeutical approach has yet been found to prevent aseptic lo...

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Detalhes bibliográficos
Publicado no:Int J Nanomedicine
Main Authors: Rivera, Melissa C, Perni, Stefano, Sloan, Alastair, Prokopovich, Polina
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6371946/
https://ncbi.nlm.nih.gov/pubmed/30804671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S188193
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