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Population Pharmacokinetic Model of Oxfendazole and Metabolites in Healthy Adults following Single Ascending Doses

Oxfendazole is a potent veterinary benzimidazole anthelmintic under transition to humans for the treatment of multiple parasitic infectious diseases. The first-in-human study evaluating the disposition of oxfendazole and its metabolites in healthy adults following single ascending oral doses from 0....

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bach, Thanh, Murry, Daryl J., Stebounova, Larissa V., Deye, Gregory, Winokur, Patricia, An, Guohua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097468/
https://ncbi.nlm.nih.gov/pubmed/33526484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02129-20
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