Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Adults in an Open-Label Phase 1 Multiple Ascending Dose and Food Effect Study

Neurocysticercosis and trichuriasis are difficult-to-treat parasitic infections that affect more than 1.5 billion people worldwide. Oxfendazole, a potent broad-spectrum benzimidazole anthelmintic approved for use in veterinary medicine, has shown substantial antiparasitic activity against neurocysti...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Bach, Thanh, Galbiati, Shirley, Kennedy, Jessie K., Deye, Gregory, Nomicos, Effie Y. H., Codd, Ellen E., Garcia, Hector H., Horton, John, Gilman, Robert H., Gonzalez, Armando E., Winokur, Patricia, An, Guohua
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7577123/
https://ncbi.nlm.nih.gov/pubmed/32816721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01018-20
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