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Pharmacokinetics, Safety, and Tolerability of Oxfendazole in Healthy Volunteers: a Randomized, Placebo-Controlled First-in-Human Single-Dose Escalation Study

Cysticercosis is a parasitic disease that frequently involves the human central nervous system (CNS), and current treatment options are limited. Oxfendazole, a veterinary medicine belonging to the benzimidazole family of anthelmintic drugs, has demonstrated substantial activity against the tissue st...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: An, Guohua, Murry, Daryl J., Gajurel, Kiran, Bach, Thanh, Deye, Greg, Stebounova, Larissa V., Codd, Ellen E., Horton, John, Gonzalez, Armando E., Garcia, Hector H., Ince, Dilek, Hodgson-Zingman, Denice, Nomicos, Effie Y. H., Conrad, Thomas, Kennedy, Jessie, Jones, Walt, Gilman, Robert H., Winokur, Patricia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6437481/
https://ncbi.nlm.nih.gov/pubmed/30745383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02255-18
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