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Pharmacokinetics and Safety of Intravenous Ceftolozane-Tazobactam in Healthy Adult Subjects following Single and Multiple Ascending Doses

The pharmacokinetics and safety of ceftolozane, a novel cephalosporin, and tazobactam, a β-lactamase inhibitor, alone and in combination as a 2:1 ratio in single doses of up to 2,000 and 1,000 mg of ceftolozane and tazobactam, respectively, and multiple doses of up to 3,000 and 1,500 mg of ceftoloza...

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Detalhes bibliográficos
Main Authors: Miller, Benjamin, Hershberger, Ellie, Benziger, David, Trinh, MyMy, Friedland, Ian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370713/
https://ncbi.nlm.nih.gov/pubmed/22450972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06349-11
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