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Impact of Renal Function on the Pharmacokinetics and Safety of Ceftolozane-Tazobactam
Ceftolozane-tazobactam is a novel antipseudomonal cephalosporin with a β-lactamase inhibitor. We investigated the pharmacokinetics (PK) and safety of ceftolozane-tazobactam in subjects with various degrees of renal function. In two phase I, open-label studies, a single dose of ceftolozane-tazobactam...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4023800/ https://ncbi.nlm.nih.gov/pubmed/24492369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02151-13 |
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