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Synergistic Rifabutin and Colistin Reduce Emergence of Resistance When Treating Acinetobacter baumannii

Recently, we reported rifabutin hyperactivity against Acinetobacter baumannii. We sought to characterize potential interactions between rifabutin and colistin, the last-resort drug for carbapenem-resistant infections. Rifabutin and colistin were synergistic in vitro and in vivo, and low-dose colisti...

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書目詳細資料
發表在:Antimicrob Agents Chemother
Main Authors: Cheng, Jiaqi, Yan, Jun, Reyna, Zeferino, Slarve, Matt, Lu, Peggy, Spellberg, Brad, Luna, Brian
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2021
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097462/
https://ncbi.nlm.nih.gov/pubmed/33468472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02204-20
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