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A Nutrient-limited Screen Unmasks Rifabutin Hyperactivity for XDR Acinetobacter baumannii

Industry screens of large chemical libraries traditionally have relied on rich media to ensure rapid bacterial growth in high-throughput testing. We used eukaryotic, nutrient-limited growth media in a compound screen that unmasked a previously unknown hyper-activity of the old antibiotic, rifabutin...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Nat Microbiol
Egile Nagusiak: Luna, B., Trebosc, V., Lee, B., Bakowski, M., Ulhaq, A., Yan, J., Lu, P., Cheng, J., Nielsen, T., Lim, J., Ketphan, W., Eoh, H., McNamara, C., Skandalis, N., She, R., Kemmer, C., Lociuro, S., Dale, G. E., Spellberg, B.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7483275/
https://ncbi.nlm.nih.gov/pubmed/32514072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41564-020-0737-6
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