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Synergistic Rifabutin and Colistin Reduce Emergence of Resistance When Treating Acinetobacter baumannii

Recently, we reported rifabutin hyperactivity against Acinetobacter baumannii. We sought to characterize potential interactions between rifabutin and colistin, the last-resort drug for carbapenem-resistant infections. Rifabutin and colistin were synergistic in vitro and in vivo, and low-dose colisti...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Cheng, Jiaqi, Yan, Jun, Reyna, Zeferino, Slarve, Matt, Lu, Peggy, Spellberg, Brad, Luna, Brian
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2021
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097462/
https://ncbi.nlm.nih.gov/pubmed/33468472
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02204-20
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