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Therapeutic Potential of Fosmanogepix (APX001) for Intra-abdominal Candidiasis: from Lesion Penetration to Efficacy in a Mouse Model

Intra-abdominal candidiasis (IAC) is one of the most common yet underappreciated forms of invasive candidiasis. IAC is difficult to treat, and therapeutic failure and drug-resistant breakthrough infections are common in some institutions despite the use of echinocandins as first-line agents. Fosmano...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Antimicrob Agents Chemother
Main Authors: Lee, Annie, Wang, Ning, Carter, Claire L., Zimmerman, Matthew, Dartois, Véronique, Shaw, Karen Joy, Perlin, David S., Zhao, Yanan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology 2021
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC8097442/
https://ncbi.nlm.nih.gov/pubmed/33468476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02476-20
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