Penetration of Ibrexafungerp (Formerly SCY-078) at the Site of Infection in an Intra-abdominal Candidiasis Mouse Model

Ibrexafungerp (IBX), formerly SCY-078, is a novel, oral and intravenous, semisynthetic triterpenoid glucan synthase inhibitor in clinical development for treating multiple fungal infections, including invasive candidiasis. Intra-abdominal candidiasis (IAC) is one of the most common types of invasive...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Lee, Annie, Prideaux, Brendan, Zimmerman, Matthew, Carter, Claire, Barat, Stephen, Angulo, David, Dartois, Véronique, Perlin, David S., Zhao, Yanan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2020
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7038262/
https://ncbi.nlm.nih.gov/pubmed/31871074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02268-19
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