Characterization of Frequently Mutated Cancer Genes and Tumor Mutation Burden in Chinese Breast Cancer

OBJECTIVES: Various genomic alterations and genomic signatures, including ERBB2 amplification, mutations in PIK3CA, AKT1, and ESR1, and tumor mutational burden (TMB), have become important biomarkers for treatment selection in breast cancer (BC). This study aimed to investigate the mutational featur...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Xiao, Weikai, Zhang, Guochun, Chen, Bo, Chen, Xiaoqing, Wen, Lingzhu, Lai, Jianguo, Li, Xuerui, Li, Min, Liu, Hao, Liu, Jing, Han-Zhang, Han, Lizaso, Analyn, Liao, Ning
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2021
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096980/
https://ncbi.nlm.nih.gov/pubmed/33968723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.618767
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