Mutational Landscape of PI3K-AKT-mTOR Pathway in Breast Cancer: Implications for Targeted Therapeutics

Background: Comprehensive analysis of PI3K-AKT-mTOR pathway gene alterations in breast cancer may be helpful for targeted therapy. Methods: We performed targeted sequencing using a panel of 520 cancer-related genes to investigate gene alterations in the PI3K-AKT-mTOR pathway from 589 consecutive Chi...

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Publicado en:J Cancer
Autores principales: Xiao, Weikai, Zhang, Guochun, Chen, Bo, Chen, Xiaoqing, Wen, Lingzhu, Lai, Jianguo, Li, Xuerui, Li, Min, Liu, Hao, Liu, Jing, Han-Zhang, Han, Lizaso, Analyn, Liao, Ning
Formato: Artigo
Lenguaje:Inglês
Publicado: Ivyspring International Publisher 2021
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8176410/
https://ncbi.nlm.nih.gov/pubmed/34093841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/jca.52993
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