Characterization of Frequently Mutated Cancer Genes and Tumor Mutation Burden in Chinese Breast Cancer

OBJECTIVES: Various genomic alterations and genomic signatures, including ERBB2 amplification, mutations in PIK3CA, AKT1, and ESR1, and tumor mutational burden (TMB), have become important biomarkers for treatment selection in breast cancer (BC). This study aimed to investigate the mutational featur...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Xiao, Weikai, Zhang, Guochun, Chen, Bo, Chen, Xiaoqing, Wen, Lingzhu, Lai, Jianguo, Li, Xuerui, Li, Min, Liu, Hao, Liu, Jing, Han-Zhang, Han, Lizaso, Analyn, Liao, Ning
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096980/
https://ncbi.nlm.nih.gov/pubmed/33968723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.618767
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