Characterization of Frequently Mutated Cancer Genes and Tumor Mutation Burden in Chinese Breast Cancer

OBJECTIVES: Various genomic alterations and genomic signatures, including ERBB2 amplification, mutations in PIK3CA, AKT1, and ESR1, and tumor mutational burden (TMB), have become important biomarkers for treatment selection in breast cancer (BC). This study aimed to investigate the mutational featur...

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Bibliografiska uppgifter
I publikationen:Front Oncol
Huvudupphovsmän: Xiao, Weikai, Zhang, Guochun, Chen, Bo, Chen, Xiaoqing, Wen, Lingzhu, Lai, Jianguo, Li, Xuerui, Li, Min, Liu, Hao, Liu, Jing, Han-Zhang, Han, Lizaso, Analyn, Liao, Ning
Materialtyp: Artigo
Språk:Inglês
Publicerad: Frontiers Media S.A. 2021
Ämnen:
Oncology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC8096980/
https://ncbi.nlm.nih.gov/pubmed/33968723
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.618767
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