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Predominant Expression of Mutant EGFR (EGFRvIII) is Rare in Primary Glioblastomas

EGFR amplification is a frequent genetic alteration in primary (de novo) glioblastomas, and is often associated with structural alterations. Most common is variant III (EGFRvIII), which results from a non‐random 801 bp in‐frame deletion of exons 2 to 7 of the EGFR gene. We assessed amplification and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Brain Pathol
Main Authors: Biernat, Wojciech, Huang, Hervé, Yokoo, Hideaki, Kleihues, Paul, Ohgaki, Hiroko
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Publishing Ltd 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095894/
https://ncbi.nlm.nih.gov/pubmed/15193025
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2004.tb00045.x
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