Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas

BACKGROUND: The efficacy of novel targeted therapies is often tested at the time of tumor recurrence. However, for glioblastoma (GBM) patients, surgical resections at recurrence are performed only in a minority of patients; therefore, molecular data are predominantly derived from the initial tumor....

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Enregistré dans:
Détails bibliographiques
Publié dans:Neuro Oncol
Auteurs principaux: van den Bent, Martin J., Gao, Ya, Kerkhof, Melissa, Kros, Johan M., Gorlia, Thierry, van Zwieten, Kitty, Prince, Jory, van Duinen, Sjoerd, Sillevis Smitt, Peter A., Taphoorn, Martin, French, Pim J.
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2015
Sujets:
Basic and Translational Investigations
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762005/
https://ncbi.nlm.nih.gov/pubmed/25691693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov013
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