Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas

BACKGROUND: The efficacy of novel targeted therapies is often tested at the time of tumor recurrence. However, for glioblastoma (GBM) patients, surgical resections at recurrence are performed only in a minority of patients; therefore, molecular data are predominantly derived from the initial tumor....

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: van den Bent, Martin J., Gao, Ya, Kerkhof, Melissa, Kros, Johan M., Gorlia, Thierry, van Zwieten, Kitty, Prince, Jory, van Duinen, Sjoerd, Sillevis Smitt, Peter A., Taphoorn, Martin, French, Pim J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762005/
https://ncbi.nlm.nih.gov/pubmed/25691693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov013
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