Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas

BACKGROUND: The efficacy of novel targeted therapies is often tested at the time of tumor recurrence. However, for glioblastoma (GBM) patients, surgical resections at recurrence are performed only in a minority of patients; therefore, molecular data are predominantly derived from the initial tumor....

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發表在:Neuro Oncol
Main Authors: van den Bent, Martin J., Gao, Ya, Kerkhof, Melissa, Kros, Johan M., Gorlia, Thierry, van Zwieten, Kitty, Prince, Jory, van Duinen, Sjoerd, Sillevis Smitt, Peter A., Taphoorn, Martin, French, Pim J.
格式: Artigo
語言:Inglês
出版: Oxford University Press 2015
主題:
Basic and Translational Investigations
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762005/
https://ncbi.nlm.nih.gov/pubmed/25691693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov013
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