Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas

BACKGROUND: The efficacy of novel targeted therapies is often tested at the time of tumor recurrence. However, for glioblastoma (GBM) patients, surgical resections at recurrence are performed only in a minority of patients; therefore, molecular data are predominantly derived from the initial tumor....

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Publicado en:Neuro Oncol
Autores principales: van den Bent, Martin J., Gao, Ya, Kerkhof, Melissa, Kros, Johan M., Gorlia, Thierry, van Zwieten, Kitty, Prince, Jory, van Duinen, Sjoerd, Sillevis Smitt, Peter A., Taphoorn, Martin, French, Pim J.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2015
Materias:
Basic and Translational Investigations
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762005/
https://ncbi.nlm.nih.gov/pubmed/25691693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov013
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