Changes in the EGFR amplification and EGFRvIII expression between paired primary and recurrent glioblastomas

BACKGROUND: The efficacy of novel targeted therapies is often tested at the time of tumor recurrence. However, for glioblastoma (GBM) patients, surgical resections at recurrence are performed only in a minority of patients; therefore, molecular data are predominantly derived from the initial tumor....

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neuro Oncol
Hauptverfasser: van den Bent, Martin J., Gao, Ya, Kerkhof, Melissa, Kros, Johan M., Gorlia, Thierry, van Zwieten, Kitty, Prince, Jory, van Duinen, Sjoerd, Sillevis Smitt, Peter A., Taphoorn, Martin, French, Pim J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2015
Schlagworte:
Basic and Translational Investigations
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5762005/
https://ncbi.nlm.nih.gov/pubmed/25691693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nov013
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