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EGFR cooperates with EGFRvIII to recruit macrophages in glioblastoma

Amplification of the EGFR gene and its truncation mutant EGFRvIII are hallmarks of glioblastoma. Although co-expression of EGFR and EGFRvIII confers a growth advantage, how EGFR and EGFRvIII influence the tumor microenvironment remains incompletely understood. Here we show that EGFR and EGFRvIII coo...

詳細記述

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書誌詳細
出版年:Cancer Res
主要な著者: An, Zhenyi, Knobbe-Thomsen, Christiane B., Wan, Xiaohua, Fan, Qi Wen, Reifenberger, Guido, Weiss, William A.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6295222/
https://ncbi.nlm.nih.gov/pubmed/30401716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3551
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