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TMIC-51. EGFR AND EGFRvIII UPREGULATE MACROPHAGE INFILTRATION IN GLIOBLASTOMA THROUGH TLR2
Amplification of the EGFR gene is identified in over half of glioblastoma (GBM) patients, with about a third of EGFR-amplified tumors co-amplify EGFRvIII, a tumor-derived allele that is constitutively active. We previously reported that co-expression of EGFR and EGFRvIII promoted growth of glioblast...
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| Publicado en: | Neuro Oncol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Oxford University Press
2017
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5692921/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nox168.1039 |
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