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Current Therapeutic Advances Targeting EGFR and EGFRvIII in Glioblastoma
Epidermal growth factor receptor (EGFR) and EGFRvIII analysis is of current interest in glioblastoma – the most common malignant primary CNS tumor, because of new EGFRvIII vaccine trials underway. EGFR activation in glioblastoma promotes cellular proliferation via activation of MAPK and PI3K–Akt pat...
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| 出版年: | Front Oncol |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310282/ https://ncbi.nlm.nih.gov/pubmed/25688333 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00005 |
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