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Caspase‐cleaved Amyloid Precursor Protein in Alzheimer's Disease

Caspase‐3 mediated cleavage of the amyloid precursor protein (APP) has been proposed as a putative mechanism underlying amyloidosis and neuronal cell death in Alzheimer's disease (AD). We utilized an antibody that selectively recognizes the neo epitope generated by caspase‐3 mediated cleavage o...

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Détails bibliographiques
Publié dans:Brain Pathol
Auteurs principaux: Ayala‐Grosso, Carlos, Ng, Gordon, Roy, Sophie, Robertson, George S
Format: Artigo
Langue:Inglês
Publié: Blackwell Publishing Ltd 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8095892/
https://ncbi.nlm.nih.gov/pubmed/12408229
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1750-3639.2002.tb00460.x
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