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Dissociation of functional and structural plasticity of dendritic spines during NMDAR and mGluR-dependent long-term synaptic depression in wild-type and fragile X model mice
Many neurodevelopmental disorders are characterized by impaired functional synaptic plasticity and abnormal dendritic spine morphology, but little is known about how these are related. Previous work in the Fmr1(-/y) mouse model of fragile X (FX) suggests that increased constitutive dendritic protein...
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| Veröffentlicht in: | Mol Psychiatry |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8095717/ https://ncbi.nlm.nih.gov/pubmed/32606374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-020-0821-6 |
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